Last night I lost a bunch of clear moonless hours because passing clouds obscured my target for a few minutes.
The guider got lost, wandered around in the clouds for a few frames, then found a new guide star and stayed locked on for the rest of the night. Unfortunately my target was way off center by then and I had to throw out more than 100 nice clear well-guided frames. I would've expected Ekos to recenter on meridian flip, but it didn't.
I see there's an open issue #77 for 3.5.4 "recenter after guiding failure," but it's unassigned. Bummer!
Maybe a fallback would be "re-center on autofocus?"
I would love extra resiliency too. Until then, there is an option to re-align at the beginning of each job. So you simply have short sequence and let the scheduler repeat it indefinitely or until certain time. In case when guider locks in wrong direction, you would only have a few remaining subs misaligned, then it re-aligns and continues nicely. My sequences are like 18×60s or 36×15s. Once in a while I get that cloud and the scheduler recovers soon enough.