The important point is that certain settings, like which profile to use, or whether to use position, or whether to use scale, can certainly speed up the solver, they also come at a cost. If you tell it to use the scale or position, but the scale or position you give it is really incorrect (outside the range of error your profile considers acceptable) then it will not solve at all. So if you find it is not solving, then unselecting or changing those parameters can allow it to solve. My suggestion is to use the profile that tends to work best for you, and to leave the scale and position options turned on. But if it does fail to solve, uncheck them and try again.

If I had to take a guess based on the RA and DEC in the file you posted, what you may have done was that the scope thought it was pointing north, but then you moved it to the target without a slew command perhaps, so it thought was still pointing north but really it was not. This is just a guess. As a rule I turn on my mount in the home position, then I slew to a bright star, then I plate solve, then I go to my target and plate solve again.

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