Hello Alain,
first of all, thank you so much your detailed answer.
My setup is as per you visualize
I've monitored the serial connection but, I only got "06"
I also tested the USB serial connection with minicom, and it is working as expected.
also checked the user group settings, my user account is under dialout group as you suggested.

It would be because of ubuntu mate image which I am using, I will try another OS to be sure.
every time USB adapter replugged, its tty name is changed accordinly, this is very annoying
I learned that there is a way to fix it playing with udev rules, but it took too much time for me by now.
I will feedback soon if I get any progress...
regards,

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