You could of course just try adding a 2nd "imagine Rpi" RPI4 (1gb maybe) and run the camera on that RPI by itself.
Its just a case of then "chaining" the 2 Indiserver's together if you use Ekos (dont need to do this with CCDCIEL or if you use Firecapture Oacapture stand alone on the "imagine RPI4"). As the comms between the 2 RPI's would be using ethernet(preferably wired) the USB device "hogging" the "Imagine Rpi" will not matter as much.

Indi has the ability to "chain" by default - unless it has been removed since I last used chaining a couple of years ago now.

There is of course a limit to what the RPI4's hardware can do no matter what you do to limit bottle necks! - then its upgrade time to something else more powerful.

Just a thought!

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