I am testing latest OSX beta (Build: 2022-09-17T18:07:01Z). It seems that it does not like duplicated drivers...
I wanted to check dual camera setup with simulators (if not simultaneous, at least alternative). I created a driver alias of the CCD Simulator driver and named it 'CCD Simulator_2'.
I then added it in a profile as Aux1 (since there's no other option right now) and CCD Simulator as main CCD camera. The result was that the Optical Trains interface stopped working. It did not appear when connecting drivers, and when called, it was blank, and it closed the app when clicking the '+' button to add a train.
This also happened when modifying an existing profile with just one camera when adding the alias as Aux, not just with new profiles.
I guess it is easy to reproduce. If you need any more info, just let me know.