I have the same problem, it is driving me crazy, using the N / S / E / W controls it moves in the correct directions with all the applications, but from CdC, Kstars, etc. the same thing happens to me,
It parks well, I point to one star, I tell him to move to one that is visually up in the sky and moves as if it were down, the same, if I point to one that is down it moves up, all the time like this.
Reinstall astroberry in RBPi4, reconfigure everything and it stays the same
I use Astroberry, EQMod, EQ5 and AstroEQ, I live in the south hemispere, in Argentina