OK so this is a very interesting one, an odd one really... I am now able to connect and this is how I've done it:
First I tried all kind of combinations, auto search, specified the serial-id, the ports etc... nothing would work so I decided to check again my Odroid and the Pegasus was symlinked to /dev/ttyUSB1 so I decided to use this in the 'ports' and hit 'save' in the indi panel.
Right after I hit the save button, I was able to connect. I've have now disconnected and reconnected multi times and no further issues.

Could you please try from your side the above "trick"

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