I have just tested with the latest nightly build of INDI and KSTARS.
I have a QHY163m and QHY 5L-II mono and there are no major issues or changes since mid-April. Cooling stays within 0.2 C within a minute or two. No issues with downloads or any other camera functionality. I'd like the cooling tightened a bit more, but I can work with it now. After 5 minutes, it more or less stays within 0.1 C with an odd excursion to 0.2 C. The QHY5L-II connects to a remote PHD2 instance using INDI and also work well. It's been stable now for quite some time.