hi pep!
well - ttySx is he standard UART, the old style miniDIN 9 COM1 port hardly to be found on any computer anymore (the pi still ha it via dedicated GPIO pins, but no direct connector). the ttyACMx thing - well - i don't think that this is the problem as your cp2102/9 hooks up to ttyUSB0. maybe a try with the pi3+ might shed more light on that problem ...
yours wolfi

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