I just got my first mount last week, a small grade from my 1960's Tasco. I discovered Astroberry and have been running my CEM40, over USB2, for several days with no problems however last night it quit working with an error "Failed to connect to port (/dev/ttyUSB1) Error Port Failure ERROR no such file..."
Checking with lsusb I get
astroberry@astroberry:~ $ lsusb
Bus 001 Device 008: ID 0403:6015 Future Technology Devices International, Ltd Bridge(I2C/SPI/UART/FIFO)
Bus 001 Device 007: ID 1233:1455 Denver Electronics
Bus 001 Device 005: ID 0130:1466
Bus 001 Device 004: ID 1a40:0101 Terminus Technology Inc. Hub
Bus 001 Device 006: ID 0424:7800 Standard Microsystems Corp.
Bus 001 Device 003: ID 0424:2514 Standard Microsystems Corp. USB 2.0 Hub
Bus 001 Device 002: ID 0424:2514 Standard Microsystems Corp. USB 2.0 Hub
Bus 001 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub

I tried two builds of Astroberry on an RPI3B and RPI4 with identical results. I contacted iOptron and got the quick reply "We received some reports about unstable connection of CEM40 to Raspberry Pi, i.e. ASIAIR; it might connect one time but fail another time. You may try the same with Windows. "
I tried windows and it works fine.

So I have a couple of question for anyone that can help. Has anybody heard of this. I would seem to impact StellerMate and other products if it is a RPI issue. Do I need to abandon the RPI and use a windows machine? If so how do I put INDI on the PC?

My nirvana would be to run everything from my Mac remotely but I also have a Windows VM and can get something for the mount. It would be best if I could run everything, like iPolar, without having 3 machines. My camera is a Sony A7R4 and EKOS/INDI seems to do almost everything, almost.