I have a cooled ASI 294MC Pro and I tried it on the Raspi with USB2 and on an Intel NUC with USB3. I didn't see any difference in image quality but the speed difference was enormous. I still use the Raspi because it's light, compact and has enough USB ports for my needs. The NUC plus USB hub would be too much for my mount.
The Rock64Pro looks like a good alternative, especially because it runs on 12V power and it has an RTC.
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