I've been using a ZWO main camera and a ZWO guide camera and it has been working well. I just use the ZWO CCD device selection in the Profile for both the CCD and the Guider. I have noticed when I occasionally have to look back at the profile that the Guider selection is blank but it hasn't had an impact on my imaging or guiding. I tried using the ZWO Camera 1, Camera 2, etc. devices but that turned out not to work well for me - in fairness I haven't even tried to use those in many months.